Date: 10 months ago   Category: Hi-Tech

The experimental immunotherapy of HIV has passed the first stage of tests of safety


Preliminary results of the first phase of clinical tests have shown safety and shipping of the cellular therapy including an expression of T-cages of ex Vivo and the subsequent introduction to HIV-positive people who were treated by means of antiretroviral therapy earlier. The research was published on September 21 in the Molecular Therapy magazine. "This research is devoted to search of a way of training of immune system of an organism for the best battle with HIV infection", the author of a research David Margolis from the University of North Carolina in Chapel-Hill says. "We have found out that this approach to retraining of immune cages and their introduction were safe that was a main objective of a research. Data of it of tests will help us with creation of the improved methods of treatment of HIV". Perspective therapy of HIV Antiretroviral therapy has turned doomed to death in chronically sick. But it not final treatment, and a virus continues to disappear from immune system. Approaches with application of pharmacological means can force a latent virus to expressirovat virus protein that will make his tank vulnerable for T-cages. But the people treated with the help the ART haven't enough existing HIV-focused immune answers to overcome a disease even in the presence of the agents inducing a HIV expression.

One of safe procedures of a call at T-cages of answers for fight against HIV is a reception cellular therapy. It includes collecting T-cages at the patient, their cultivation in laboratory for increase in number and return to the patient that those helped immune system to struggle with a disease. The first approaches with reception T-cellular therapy for HIV showed low efficiency for various reasons. But since then this area has seen many breaks, mostly in the field of oncology, and now this procedure can be already not only safe, but also highly effective.

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