Date: 2 weeks ago   Category: Hi-Tech

The algorithm of artificial intelligence is developed for exact editing a genome


Scientists from the Massachusetts Institute of Technology and Harvard University have developed an algorithm of machine learning which with high precision can predict result of editing a genome by means of CRISPR-Cas9 technology. Writes Science Daily about it.

have opened CRISPR/Cas9 Technology in 2013 as the mechanism of bacterial immunity of virus DNA. These "molecular scissors" allow to cut out and change sites of DNA of any organisms directly in living cells. Now genomic editing is tested as therapy of various diseases caused by mutations.

However human genome is the natural mechanism of autocorrection - he "sews" a double spiral of DNA back if it collapses in any way - including, when using CRISPR/Cas9. And results of such repair aren't always successful: the same as automatic replacement in the smartphone can correct an unknown word on improper as well the genomic editor can add an improper fragment of DNA in the place of a gap. Because of this side effect the CRISPR/Cas9 technology, at all the prospects, for the present remains by too dangerous method of therapy.

Now scientists have created an algorithm of machine learning which foretells how human and mouse cages will react to the ruptures of DNA caused by CRISPR/Cas9. They have already successfully corrected mutations in the cages taken from patients with rare genetic genetic disorders.

was reported Earlier that scientists have deciphered wheat genome. It will allow to create more productive varieties. 0
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Tags: CRISPR-Cas9, a gene, genetic engineering, a genome, genomic editing, DNA, artificial intelligence, editing a genome

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