Date: 6 days ago   Category: Hi-Tech

Scientists have started creation of a new class of antibiotics capable to kill superbacteria


Scientists have started creation of a new class of antibiotics capable to kill superbacteria
Recently druggists are more and more concerned about emergence, so-called, superbacteria - the microorganisms steady against influence of the majority of the known antibiotics. And for their destruction it is necessary to create "superantibiotics". The group of the Danish bacteriologists was also engaged in it.

As reports the Nature edition, doctor Hans Christiaan Graham from the Genentech company heads a research. Development is conducted within the G0775 project.

On one of classifications, bacteria are divided into 2 types: grampolozhitelny and gramotritsatelny. The first in the structure have an external membrane which interferes with penetration of alien agents inside. It gives them stability, however on a surface of this membrane is located пептидогликан which is a target for antibiotics. Bacteria from the second category have пептидогликан too, but he "is hidden" between two membranes that extremely complicates fight against such microorganisms.

exist Already today some "superantibiotics" which cornerstone substance of a class of arilomitsin which block the enzymes important for activity of bacteria is, getting through cellular walls. The new molecule G0775 is much more effective than existing. She has much more best permeability. G0775 have already tested on Klebsiella Pneumoniae strain, steady against 13 antibiotics. And G0775 has shown high efficiency. But, despite positive results, before creation of new medicine it is still far. As researchers note, "Still early to claim that opening of new type of the connection capable to block alarm processes will turn medicine in the nearest future. Similar antibiotics appear very seldom. Now we will continue to modify G0775 for destruction of other strains of bacteria which usual antibiotics don't influence any more."

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