Date: 10 months ago   Category: Health

Geneticists approved a new method of editing human genome


The American officials have approved the first medicine based on the principle of a RNA interference. It is the method allowing "to muffle" work of the genes causing a dangerous disease broadcasts "News of Mail.RU". Means is designed to treat transtiretinovy амилоидоз. This serious hereditary illness which is characterized by damage of a liver.

the Essence of a method consists in the following: from each working gene MRNK which then is delivered from a kernel in cage cytoplasm, to "proteinaceous factories" of a ribosome where according to the instruction of this MRNK protein is synthesized is read out. If you want to break this process, it is required to stop MRNK somewhere halfway to a ribosome.

can Make it if in a cage other RNA capable to form with her a double chain appears. The cage destroys such products at once. Thus, for "muting" of work of a gene just the fragment of this gene needs to enter into the cell of RNA identical on the sequence.

However RNA differs in low stability. The problem managed to be solved, having placed it in fatty nanoparticles. Particles collected in a liver and kidneys. This fact has influenced the choice of target illnesses (so far the method works against illnesses at which the expression of genes in a liver is broken).

URL:




Today

just now

Producers of kosher products give a 100-protsenty quality assurance of meat, milk, vegetables and bread. For quite some time now in the capital of Russia appeared a new trend under the name "Kosher...

just now

Hundreds of representatives of flora and fauna of Slobozhanshchina on the verge of disappearance. All of them are unique as all of them are included in the Red List. Ecologists counted: it is about 38...

just now

Specialists of the Ukrtransnafta company found per day and liquidated three illegal inserts, two of which were in the main Druzhba Pipeline. On Saturday the press service of the enterprise in Facebook...

just now

The sportswoman was noticed when landing to a personal business jet in St. Petersburg after defense of a thesis. attribute to the Famous Russian gymnast Alina Kabayeva the novel in the President of...

just now

The rhetoric of the new Ukrainian leader creates prerequisites for advance of the Minsk process, however progress can achieve only in case of steps towards Moscow and support of the international comm...

just now

In the modern world of technology bear the same destructive force, as well as weapon. It is in the battlefield already difficult to do without the new systems of navigation and positioning which not o...

just now

The forward of Argentina national team Lionel Messi shared impressions after defeat of Colombia (0:2) in a match of the first round of the Cup of America. "I think, in this match there were good poi...

just now

About two o'clock in the morning on the route between Novoalekseevkaya and Genichesk, on 195 km of the highway "Kherson-Kakhovka-Genichesk", there was a road accident with serious consequences. the...